abstract |
CRISPR-Cas9 has revolutionized genetic manipulation in unprecedented ways, as it
is an inexpensive, precise, and fast means of editing genes. The CRISPR-Cas9 system has
been exploited to alter DNA in various organisms and human embryos. Editing the human
genome has the potential to become a reality, thus theoretically enabling scientists to
correct disease-causing mutations in human DNA. However, this revolutionary technique
has serious ethical considerations. Before employing CRISPR-Cas9 for human medical
treatments, the four tenets of biomedical ethics need to be addressed for all stakeholders.
Other considerations for moving forward include the influence of societal values and laws
governing such practices. Ethical issues surrounding gene editing in humans are vividly and thoroughly
depicted in various works of science fiction. Although the science may or may not be in
alignment with current technologies, the social and ethical warnings presented in science
fiction are undeniable. Science fiction can serve as a tool to educate future scientists on
how to ethically evaluate research projects to ensure ethical standards are met and consider
the social impacts discoveries might have. Lastly, science fiction can be a visualization tool
in guiding regulations that need to be implemented now while technologies are advancing
to prevent ethical violations.
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