| |
| author |
Violet Wallerstein
| | title |
Don't Break a Leg: The Effects of Vitamin D Intervention and Lactose Intolerance on the Bone Health of Pediatric Patients
| | abstract |
This study is a longitudinal study that aims to determine whether providing
supplemental vitamin D will increase total BMC and BMD in pediatric patients that have
experienced a fracture, taking into account how lactose intolerance may impact pediatric
bone health. Pediatric fracture patients that had low vitamin D serum levels were given
vitamin D supplements to increase their serum levels. Patients got a DXA scan 12 weeks,
6 months, and 12 months post-fracture where lumbar spine (LS) and total body less head
(TBLH) bone mineral content (BMC) and bone mineral density (BMD) were measured.
Height-adjusted z-scores (HAZs) for the data at each time point were calculated. A total
of 17 patients out of 55 enrolled completed all three scans. There was no significant
difference in HAZs from the first scan to the third scan. The average HAZs at the LS had
a decrease from the first to third scan, whereas TBLH measurements had an increase in
average HAZs. Tanner stage was shown to have a large impact on the data with R2 values
above 0.25 for all measurements. No conclusions could be drawn about the impact of
lactose intolerance on bone health due to a small sample size (n=2).
| | school |
The College of Liberal Arts, Drew University
| | degree |
B.S. (2020)
|
| advisor |
Roger Knowles
|
| full text | VWallerstein.pdf |
| |
